Cidec^tm1Pli
Targeted Allele Detail

Summary

• Symbol: Cidec^tm1Pli
• Name: cell death-inducing DFFA-like effector c; targeted mutation 1, Peng Li
• MGI ID: MGI:3812467
• Synonyms: Fsp27^-
• Gene: Cidec Location: Chr6:113401595-113412721 bp, - strand Genetic Position: Chr6, 52.76 cM, cytoband E3
• Alliance: Cidec^tm1Pli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:140122
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: All of exon 2, which contains the translation initiation site, and part of exon 3 were replaced with a neomycin selection cassette in the opposite orientation. Gene inactivation was confirmed by a lack of protein in white- and brown- adipbose tissue, as determined by immunoblotting. (J:140122)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cidec Mutation: 15 strains or lines available

References

• Original: J:140122 Toh SY, et al., Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice. PLoS One. 2008;3(8):e2890
• All: 9 reference(s)