Tg(Alb-REG3A)24Lchr
Transgene Detail

Summary

• Symbol: Tg(Alb-REG3A)24Lchr
• Name: transgene insertion 24, Laurence Christa
• MGI ID: MGI:3812483
• Synonyms: Tg(Alb-REG2)24Lchr
• Transgene: Tg(Alb-REG3A)24Lchr Location: unknown
• Alliance: Tg(Alb-REG3A)24Lchr page

Transgene origin

• Strain of Origin: C57BL/6 x CBA

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Alb-REG3A)24Lchr expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  REG3A (5068)

  Reg3a	(MGI:109408)
  Reg3b	(MGI:97478)

• Mutation details: The promoter was used to drive liver specific expression of the human gene. Lines 24 and 27 were created with line 24 chosen as the representative line. (J:84698)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:84698 Simon MT, et al., HIP/PAP stimulates liver regeneration after partial hepatectomy and combines mitogenic and anti-apoptotic functions through the PKA signaling pathway. FASEB J. 2003 Aug;17(11):1441-50
• All: 2 reference(s)