Rnf112^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Rnf112^{tm1(KOMP)Vlcg}
• Name: ring finger protein 112; targeted mutation 1, Velocigene
• MGI ID: MGI:3812654
• Synonyms: Rnf112^tm1Vlcg
• Gene: Rnf112 Location: Chr11:61339268-61344957 bp, - strand Genetic Position: Chr11, 37.96 cM, cytoband B1.3
• Alliance: Rnf112^{tm1(KOMP)Vlcg} page
• IMPC: Rnf112 gene page

Mutation origin

• Mutant Cell Lines: 10610A-A6, 10610A-F3
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 4459bp between positions 61340214-61344672 of Chromosome 11 (Build GRCm39). Western blot analysis confirmed the absence of protein expression in the brain. (J:136110, J:232515)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Rnf112 Mutation: 30 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 4 reference(s)