Oxgr1^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Oxgr1^{tm1(KOMP)Vlcg}
• Name: oxoglutarate (alpha-ketoglutarate) receptor 1; targeted mutation 1, Velocigene
• MGI ID: MGI:3812671
• Synonyms: Oxgr1^tm1Vlcg
• Gene: Oxgr1 Location: Chr14:120256997-120279847 bp, - strand Genetic Position: Chr14, 63.63 cM
• Alliance: Oxgr1^{tm1(KOMP)Vlcg} page
• IMPC: Oxgr1 gene page

Mutation origin

• Mutant Cell Lines: 10698A-C8, 10698B-F2, 10698C-B4, 10698C-C2, 10698C-D12, 10698C-E2, 10698D-A8
• Germline Transmission: Earliest citation of germline transmission: J:198383
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1443bp between positions 120258760-120260202 of Chromosome 14 (Build GRCm39). (J:136110)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Oxgr1 Mutation: 22 strains or lines available

Notes

Cell lines 10698B-F2 and 10698C-D12 were successfully used to make chimeric mice. Germline transmission of each line was accomplished. J:198383

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 11 reference(s)