Arhgef15^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Arhgef15^{tm1(KOMP)Vlcg}
• Name: Rho guanine nucleotide exchange factor 15; targeted mutation 1, Velocigene
• MGI ID: MGI:3812708
• Synonyms: Arhgef15^lacZ, Arhgef15^tm1Vlcg
• Gene: Arhgef15 Location: Chr11:68833981-68848306 bp, - strand Genetic Position: Chr11, 42.21 cM
• Alliance: Arhgef15^{tm1(KOMP)Vlcg} page
• IMPC: Arhgef15 gene page

Mutation origin

• Mutant Cell Lines: 10757A-D2, 10757B-C6, 10757B-G3
• Germline Transmission: Earliest citation of germline transmission: J:188649
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 10457bp between positions 68835391-68845847 of Chromosome 11 (Build GRCm39). The lacZ reporter is expressed instead of exon 1. (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Arhgef15 Mutation: 48 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)