Prrt1^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Prrt1^{tm1(KOMP)Vlcg}
• Name: proline-rich transmembrane protein 1; targeted mutation 1, Velocigene
• MGI ID: MGI:3812714
• Synonyms: Prrt1^tm1Vlcg
• Gene: Prrt1 Location: Chr17:34848507-34852100 bp, + strand Genetic Position: Chr17, 18.21 cM
• Alliance: Prrt1^{tm1(KOMP)Vlcg} page
• IMPC: Prrt1 gene page

Mutation origin

• Mutant Cell Lines: 10773A-D11, 10773A-G8
• Germline Transmission: Earliest citation of germline transmission: J:260353
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 2650bp between positions 34848643-34851292 of Chromosome 17 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Prrt1 Mutation: 9 strains or lines available

Notes

Cell line 10773A-D11 was successfully used to make chimeric mice. Germline transmission was accomplished. J:260353

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 3 reference(s)