Cldn18^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Cldn18^{tm1(KOMP)Vlcg}
• Name: claudin 18; targeted mutation 1, Velocigene
• MGI ID: MGI:3812813
• Synonyms: Cldn18^tm1Vlcg
• Gene: Cldn18 Location: Chr9:99572849-99599320 bp, - strand Genetic Position: Chr9, 52.0 cM, cytoband E3-F1
• Alliance: Cldn18^{tm1(KOMP)Vlcg} page
• IMPC: Cldn18 gene page

Mutation origin

• Mutant Cell Lines: 11015B-G8, 11015B-H4, 11015C-H3, 11015C-H11, 11015D-E7, 11015D-F3
• Germline Transmission: Earliest citation of germline transmission: J:232069
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 17301bp between positions 99574698-99591998 of Chromosome 9 (Build GRCm39). (J:136110)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Cldn18 Mutation: 19 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 4 reference(s)