Iscu^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Iscu^{tm1(KOMP)Vlcg}
• Name: iron-sulfur cluster assembly enzyme; targeted mutation 1, Velocigene
• MGI ID: MGI:3813096
• Synonyms: Iscu^tm1Vlcg
• Gene: Iscu Location: Chr5:113910809-113916349 bp, + strand Genetic Position: Chr5, 55.55 cM
• Alliance: Iscu^{tm1(KOMP)Vlcg} page
• IMPC: Iscu gene page

Mutation origin

• Mutant Cell Lines: 11691A-A12, 11691A-B10, 11691A-B11, 11691A-H8
• Germline Transmission: Earliest citation of germline transmission: J:339029
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 5112bp between positions 113910875-113915986 of Chromosome 5 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Iscu Mutation: 7 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)