Uba6^tm1Zjc
Targeted Allele Detail

Summary

• Symbol: Uba6^tm1Zjc
• Name: ubiquitin-like modifier activating enzyme 6; targeted mutation 1, Zhijian Chen
• MGI ID: MGI:3813907
• Synonyms: E1L2^-
• Gene: Uba6 Location: Chr5:86258579-86320602 bp, - strand Genetic Position: Chr5, 43.56 cM
• Alliance: Uba6^tm1Zjc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:140387
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to replace 5.9 kb containing exons 1 and 2 with a PGK-neomycin cassette flanked by loxP sites. (J:140387)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Uba6 Mutation: 59 strains or lines available

References

• Original: J:140387 Chiu YH, et al., E1-L2 activates both ubiquitin and FAT10. Mol Cell. 2007 Sep 21;27(6):1014-23
• All: 1 reference(s)