Tnfrsf19^{Gt(OST294987)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Tnfrsf19^{Gt(OST294987)Lex}
• Name: tumor necrosis factor receptor superfamily, member 19; gene trap OST294987, Lexicon Genetics
• MGI ID: MGI:3813972
• Synonyms: Troy^-
• Gene: Tnfrsf19 Location: Chr14:61201324-61283939 bp, - strand Genetic Position: Chr14, 32.06 cM
• Alliance: Tnfrsf19^{Gt(OST294987)Lex} page

Mutation origin

• Mutant Cell Line: OST294987
• Germline Transmission: Earliest citation of germline transmission: J:140329
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector VICTR, which contains a neo cassette, was inserted into intron 1 upstream of the translation initiation codon in exon 2. The absence of full-length transcript expression was confirmed by RT-PCR. (J:140329)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST294987	CG610826 ; (MGI Seq Detail)	3' RACE	Chr14:61234030-61262282 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  18 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:

5 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tnfrsf19 Mutation: 35 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:140329 Pispa J, et al., Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development. Hum Mol Genet. 2008 Nov 1;17(21):3380-91
• All: 3 reference(s)