Trpm7^Gt(XC765)Byg
Gene trapped Allele Detail

Summary

• Symbol: Trpm7^Gt(XC765)Byg
• Name: transient receptor potential cation channel, subfamily M, member 7; gene trap XC765, BayGenomics
• MGI ID: MGI:3814707
• Synonyms: Trpm7^geo
• Gene: Trpm7 Location: Chr2:126633485-126718150 bp, - strand Genetic Position: Chr2, 61.76 cM, cytoband F2
• Alliance: Trpm7^Gt(XC765)Byg page

Mutation origin

• Mutant Cell Line: XC765
• Germline Transmission: Earliest citation of germline transmission: J:140630
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• The gene trap vector inserted at about 3.4 kb into the intron following exon 1. (J:140630)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XC765	CC178048 ; (MGI Seq Detail)	5' RACE	Chr2:126717894-126718155 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  11 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trpm7 Mutation: 102 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:140630 Jin J, et al., Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis. Science. 2008 Oct 31;322(5902):756-60
• All: 2 reference(s)