Nectin1^tm1Mjd
Targeted Allele Detail

Summary

• Symbol: Nectin1^tm1Mjd
• Name: nectin cell adhesion molecule 1; targeted mutation 1, Michael J Dixon
• MGI ID: MGI:3814719
• Gene: Nectin1 Location: Chr9:43655251-43718758 bp, + strand Genetic Position: Chr9, 24.42 cM, cytoband B
• Alliance: Nectin1^tm1Mjd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:140568
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replace with a neo cassette. The absence of protein was confirmd by western blot analysis on embryo tissue extracts. (J:140568)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nectin1 Mutation: 23 strains or lines available

References

• Original: J:140568 Barron MJ, et al., The cell adhesion molecule nectin-1 is critical for normal enamel formation in mice. Hum Mol Genet. 2008 Nov 15;17(22):3509-20
• All: 2 reference(s)