Adgre5^tm1.1Joha
Targeted Allele Detail

Summary

• Symbol: Adgre5^tm1.1Joha
• Name: adhesion G protein-coupled receptor E5; targeted mutation 1.1, Jorg Hamann
• MGI ID: MGI:3814838
• Gene: Adgre5 Location: Chr8:84449874-84467812 bp, - strand Genetic Position: Chr8, 40.22 cM
• Alliance: Adgre5^tm1.1Joha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:140713
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove exons 2 through 5. The absence of protein expression was confirmed by western blot analysis on lung, spleen, heart and liver extracts. (J:140713)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adgre5 Mutation: 68 strains or lines available

References

• Original: J:140713 Veninga H, et al., Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration. J Immunol. 2008 Nov 1;181(9):6574-83
• All: 4 reference(s)