About   Help   FAQ
Gt(ROSA)26Sortm2.1(Cd74/MOG)Awai
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm2.1(Cd74/MOG)Awai
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2.1, Ari Waisman
MGI ID: MGI:3814860
Synonyms: IiMOG
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm2.1(Cd74/MOG)Awai page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:140751
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsCre-mediated recombination removed the STOP cassette and allow for expression of the Cd74-MOG fusion. (J:140751)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  993 strains or lines available
References
Original:  J:140751 Frommer F, et al., Tolerance without clonal expansion: self-antigen-expressing B cells program self-reactive T cells for future deletion. J Immunol. 2008 Oct 15;181(8):5748-59
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory