Zbtb7btm1Itan
Targeted Allele Detail
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| Symbol: |
Zbtb7btm1Itan |
| Name: |
zinc finger and BTB domain containing 7B; targeted mutation 1, Ichiro Taniuchi |
| MGI ID: |
MGI:3817517 |
| Synonyms: |
ThPokPEdelta |
| Gene: |
Zbtb7b Location: Chr3:89284953-89300976 bp, - strand Genetic Position: Chr3, 39.09 cM, cytoband A1-A2
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| Alliance: |
Zbtb7btm1Itan page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:141142
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| Parent Cell Line: |
M1/M-1 (ES Cell)
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| Strain of Origin: |
(129 x C57BL/6)F1
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was placed approximately 6 kb upstream of the transcription start site, placing it 5' to a proximal enhancer for this gene locus. A floxed neo-cassette was placed downstream of the enhancer. Transient expression of cre-recombinase removed a 2.2-kb region including the proximal enhancer and the neo cassette. Southern blotting confirmed correct targeting of the locus.
(J:141142)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Zbtb7b Mutation: |
26 strains or lines available
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| Original: |
J:141142 Muroi S, et al., Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate. Nat Immunol. 2008 Oct;9(10):1113-21 |
| All: |
1 reference(s) |
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Analysis Tools
