Tg(CD4-Zbtb7b*,-GFP)1Itan
Transgene Detail

Summary

• Symbol: Tg(CD4-Zbtb7b*,-GFP)1Itan
• Name: transgene insertion 1, Ichiro Taniuchi
• MGI ID: MGI:3817547
• Synonyms: FH-ThPOK^hd
• Transgene: Tg(CD4-Zbtb7b*,-GFP)1Itan Location: unknown
• Alliance: Tg(CD4-Zbtb7b*,-GFP)1Itan page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CD4-Zbtb7b*,-GFP)1Itan expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Zbtb7b (MGI:102755)

• Mutation details: The CD4 promoter drives expression of an N-terminally HA-tagged gene encoding the "helper deficient" (hd) allele of the Zbtb7b gene. An internal ribosome entry site and GFP are also included in the construct. (J:141142)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:141142 Muroi S, et al., Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate. Nat Immunol. 2008 Oct;9(10):1113-21
• All: 2 reference(s)