Atoh7^{tm1(Neurod1)Whk}
Targeted Allele Detail

Summary

• Symbol: Atoh7^{tm1(Neurod1)Whk}
• Name: atonal bHLH transcription factor 7; targeted mutation 1, William H Klein
• MGI ID: MGI:3817875
• Synonyms: Math5^Neurod1-KI
• Gene: Atoh7 Location: Chr10:62935564-62937059 bp, + strand Genetic Position: Chr10, 32.54 cM
• Alliance: Atoh7^{tm1(Neurod1)Whk} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:141248
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted
• Mutations: Insertion, Intragenic deletion
• The coding exon was replaced with that of Neurod1 and is followed by an frt-flanked neo cassette. (J:141248)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atoh7 Mutation: 9 strains or lines available

References

• Original: J:141248 Mao CA, et al., Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5. Development. 2008 Oct;135(20):3379-88
• All: 1 reference(s)