Mapk8ip3^tm1Ysok
Targeted Allele Detail

Summary

• Symbol: Mapk8ip3^tm1Ysok
• Name: mitogen-activated protein kinase 8 interacting protein 3; targeted mutation 1, Katsuji Yoshioka
• MGI ID: MGI:3818507
• Synonyms: jsap^2loxP, jsap^flox
• Gene: Mapk8ip3 Location: Chr17:25116480-25155951 bp, - strand Genetic Position: Chr17, 12.53 cM
• Alliance: Mapk8ip3^tm1Ysok page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:141459
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted downstream of exon 2 and an additional loxP site was inserted downstream of exon 4. Germ line, cre mediated recombination was used to remove the neo cassette leaving exons 3 and 4 floxed. (J:141459)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mapk8ip3 Mutation: 53 strains or lines available

References

• Original: J:141459 Iwanaga A, et al., Neural-specific ablation of the scaffold protein JSAP1 in mice causes neonatal death. Neurosci Lett. 2007 Dec 11;429(1):43-8
• All: 4 reference(s)