Mapk8ip3^tm1.1Ysok
Targeted Allele Detail

Summary

• Symbol: Mapk8ip3^tm1.1Ysok
• Name: mitogen-activated protein kinase 8 interacting protein 3; targeted mutation 1.1, Katsuji Yoshioka
• MGI ID: MGI:3818508
• Synonyms: jsap^-, jsap^1loxP
• Gene: Mapk8ip3 Location: Chr17:25116480-25155951 bp, - strand Genetic Position: Chr17, 12.53 cM
• Alliance: Mapk8ip3^tm1.1Ysok page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:141459
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove exons 3 and 4. The absence of protein expression was confirmed by western blot analysis on brain and heart extracts. (J:141459)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mapk8ip3 Mutation: 53 strains or lines available

References

• Original: J:141459 Iwanaga A, et al., Neural-specific ablation of the scaffold protein JSAP1 in mice causes neonatal death. Neurosci Lett. 2007 Dec 11;429(1):43-8
• All: 1 reference(s)