Taar1^tm1Tdw
Targeted Allele Detail

Summary

• Symbol: Taar1^tm1Tdw
• Name: trace amine-associated receptor 1; targeted mutation 1, Toni D Wolinsky
• MGI ID: MGI:3818697
• Gene: Taar1 Location: Chr10:23796304-23797302 bp, + strand Genetic Position: Chr10, 11.39 cM, cytoband A3
• Alliance: Taar1^tm1Tdw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:141501
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 3.6 kb fragment including the entire coding region along with 1.0 kb of upstream sequence and about 1.3 kb of downstream sequence were replaced with a neo cassette via homologous recombination. (J:141501)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Taar1 Mutation: 34 strains or lines available

References

• Original: J:141501 Wolinsky TD, et al., The Trace Amine 1 receptor knockout mouse: an animal model with relevance to schizophrenia. Genes Brain Behav. 2007 Oct;6(7):628-39
• All: 3 reference(s)