Tmie^sr-2J
Spontaneous Allele Detail

Summary

• Symbol: Tmie^sr-2J
• Name: transmembrane inner ear; spinner 2 Jackson
• MGI ID: MGI:3819109
• Gene: Tmie Location: Chr9:110694755-110709141 bp, - strand Genetic Position: Chr9, 60.79 cM
• Alliance: Tmie^sr-2J page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Single point mutation
• Mutation details: A G-to A-transition destroys exon 5 splice acceptor site CAG by changing it to CAA, leading to mis-splicing and absence of wild-type transcripts. (J:147860)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tmie Mutation: 15 strains or lines available

References

• Original: J:147860 Kane KL, et al., Spinner 2 Jackson, a new spontaneous mutation in the Tmie gene. MGI Direct Data Submission. 2009
• All: 2 reference(s)