Tg(APOE-DHCR7)2Hoyu
Transgene Detail

Summary

• Symbol: Tg(APOE-DHCR7)2Hoyu
• Name: transgene insertion 2, Hongwei Yu
• MGI ID: MGI:3819682
• Synonyms: TgDHCR7-2
• Transgene: Tg(APOE-DHCR7)2Hoyu Location: unknown
• Alliance: Tg(APOE-DHCR7)2Hoyu page

Transgene origin

• Strain of Origin: C57BL x FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(APOE-DHCR7)2Hoyu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  DHCR7 (1717)

  Dhcr7

  (MGI:1298378)

• Mutation details: The human promoter was used to drive liver-specific expression of the human gene. Two lines were created (line 2 and line 3) with identical patterns of expression. (J:141730)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:141730 Yu H, et al., Selective reconstitution of liver cholesterol biosynthesis promotes lung maturation but does not prevent neonatal lethality in Dhcr7 null mice. BMC Dev Biol. 2007;7:27
• All: 1 reference(s)