Tg(Lck-VIPR2)1Ejg
Transgene Detail

Summary

• Symbol: Tg(Lck-VIPR2)1Ejg
• Name: transgene insertion 1, Edward J Goetzl
• MGI ID: MGI:3819792
• Synonyms: huVPAC2 R, LCK-huVPAC2, LCK-huVPAC2R
• Transgene: Tg(Lck-VIPR2)1Ejg Location: unknown
• Alliance: Tg(Lck-VIPR2)1Ejg page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lck-VIPR2)1Ejg expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  VIPR2 (7434)

  Vipr2

  (MGI:107166)

• Mutation details: A murine lymphocyte protein tyrosine kinase (Lck) proximal promoter was used to drive the full-length human VPAC2R cDNA (huVPAC2 R or VIPR2; vasoactive intestinal peptide G-protein-coupled receptor 2). This transgene was microinjected into C57BL/6 oocytes, and a male founder animal was bred to C57BL/6 females to establish the line. (J:127974)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:127974 Voice JK, et al., Allergic diathesis in transgenic mice with constitutive T cell expression of inducible vasoactive intestinal peptide receptor. FASEB J. 2001 Nov;15(13):2489-96
• All: 3 reference(s)