Cd151^tm1Mhe
Targeted Allele Detail

Summary

• Symbol: Cd151^tm1Mhe
• Name: CD151 antigen; targeted mutation 1, Martin E Hemler
• MGI ID: MGI:3819817
• Gene: Cd151 Location: Chr7:141047305-141051386 bp, + strand Genetic Position: Chr7, 86.82 cM
• Alliance: Cd151^tm1Mhe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:141595
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This is a deletion that begins from a site in the 5' untranslated region, removes the first four coding exons and part of the fifth, and includes the first 168 amino acids (of 253). (J:141595)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd151 Mutation: 34 strains or lines available

References

• Original: J:141595 Takeda Y, et al., Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro. Blood. 2007 Feb 15;109(4):1524-32
• All: 8 reference(s)