Arhgef9^tm1Betz
Targeted Allele Detail

Summary

• Symbol: Arhgef9^tm1Betz
• Name: CDC42 guanine nucleotide exchange factor 9; targeted mutation 1, Heinrich Betz
• MGI ID: MGI:3820313
• Synonyms: Cb(+)
• Gene: Arhgef9 Location: ChrX:94092541-94240462 bp, - strand Genetic Position: ChrX, 41.85 cM
• Alliance: Arhgef9^tm1Betz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:141850
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of exon 5 and a single loxP site was inserted downstream of exon 5. The neo cassette was then removed by Cre mediated recombination leaving exon 5 floxed. (J:124926, J:141850)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arhgef9 Mutation: 7 strains or lines available

References

• Original: J:141850 Papadopoulos T, et al., Collybistin is required for both the formation and maintenance of GABAergic postsynapses in the hippocampus. Mol Cell Neurosci. 2008 Oct;39(2):161-9
• All: 2 reference(s)