Ildr2^W87*
Chemically induced Allele Detail

Summary

• Symbol: Ildr2^W87*
• Name: immunoglobulin-like domain containing receptor 2; amber stop mutation, Ingenium Pharmaceuticals
• MGI ID: MGI:3820395
• Synonyms: W87*
• Gene: Ildr2 Location: Chr1:166081708-166144392 bp, + strand Genetic Position: Chr1, 73.61 cM
• Alliance: Ildr2^W87* page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A G to A substitution was detected that causes an Amber stop mutation at Threonine-87. Protein expression was greatly reduced in the brain. (J:138216)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ildr2 Mutation: 27 strains or lines available

References

• Original: J:138216 Dokmanovic-Chouinard M, et al., Positional cloning of 'Lisch-Like', a candidate modifier of susceptibility to type 2 diabetes in mice. PLoS Genet. 2008 Jul;4(7):e1000137
• All: 1 reference(s)