Omg^tm1Shmi
Targeted Allele Detail

Summary

• Symbol: Omg^tm1Shmi
• Name: oligodendrocyte myelin glycoprotein; targeted mutation 1, Sha Mi
• MGI ID: MGI:3821628
• Synonyms: OMgp^-
• Gene: Omg Location: Chr11:79391808-79394908 bp, - strand Genetic Position: Chr11, 46.79 cM, cytoband B5
• Alliance: Omg^tm1Shmi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:142129
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding region was replaced by a GFP and neo cassette. The absence of protein expression was confirmed by western blot on brain and spinal cord extracts. (J:142129)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Omg Mutation: 20 strains or lines available

References

• Original: J:142129 Ji B, et al., Assessment of functional recovery and axonal sprouting in oligodendrocyte-myelin glycoprotein (OMgp) null mice after spinal cord injury. Mol Cell Neurosci. 2008 Oct;39(2):258-67
• All: 6 reference(s)