About   Help   FAQ
Dlgap5tm1Tfts
Targeted Allele Detail
Summary
Symbol: Dlgap5tm1Tfts
Name: DLG associated protein 5; targeted mutation 1, Ting-Fen Tsai
MGI ID: MGI:3821727
Synonyms: Hurp-
Gene: Dlgap5  Location: Chr14:47625238-47655657 bp, - strand  Genetic Position: Chr14, 24.6 cM
Alliance: Dlgap5tm1Tfts page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:142315
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette followed by a 4.47 kb genomic DNA fragment containing parts of exons 2 and 4 and all of exon 3 was inserted. Northern blot analysis confirmed the absence of mRNA expression in homozygous mice. (J:142315)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Dlgap5 Mutation:  39 strains or lines available
References
Original:  J:142315 Tsai CY, et al., Hurp deficiency in mice leads to female infertility caused by an implantation defect. J Biol Chem. 2008 Sep 26;283(39):26302-6
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory