Tg(Atoh1-lacZ)1Jejo
Transgene Detail

Summary

• Symbol: Tg(Atoh1-lacZ)1Jejo
• Name: transgene insertion 1, Jane E Johnson
• MGI ID: MGI:3821758
• Synonyms: Math1^lacZ
• Transgene: Tg(Atoh1-lacZ)1Jejo Location: unknown
• Alliance: Tg(Atoh1-lacZ)1Jejo page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: This transgene was created by coinjection of three overlapping fragments. The first fragment (SphI-SphI restriction fragment) contained 15 kb of sequence 5' to the Atoh1 coding sequence. The second (NcoI-NcoI) contained up- and downstream sequence flanking the coding sequence where the coding sequence between the first ~2.5 kb and the last ~1.5 kb was replaced in-frame with the beta-galactosidase reporter gene (without NLS sequence). The third sequence (BglII-BglII) contained the last ~400 bp of coding sequence and 6 kb 3' of the coding region. Five individuals were identified which expressed lacZ in a pattern consistent with the promoter although the expected order of recombination was not confirmed. One of these lines was maintained. (J:47081)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:47081 Helms AW, et al., Progenitors of dorsal commissural interneurons are defined by MATH1 expression. Development. 1998 Mar;125(5):919-28
• All: 7 reference(s)