Tg(CAG-cat,-Ptpn11)1Rbns
Transgene Detail

Summary

• Symbol: Tg(CAG-cat,-Ptpn11)1Rbns
• Name: transgene insertion 1, Jeffrey Robbins
• MGI ID: MGI:3822130
• Synonyms: CAGCAT-WT-Shp2
• Transgene: Tg(CAG-cat,-Ptpn11)1Rbns Location: unknown
• Alliance: Tg(CAG-cat,-Ptpn11)1Rbns page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-cat,-Ptpn11)1Rbns expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ptpn11 (MGI:99511)

• Mutation details: The ubiquitous CAG (chicken beta actin) promoter was used to drive cre-dependent expression Ptpn11 following removal of an intervening floxed chloramphenicol (cat) gene. Several lines were created with similar expression patterns. (No line names given) (J:142212)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:142212 Krenz M, et al., Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome. Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18930-5
• All: 1 reference(s)