Mir133a-1tm1.1Eno
Targeted Allele Detail
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Symbol: |
Mir133a-1tm1.1Eno |
Name: |
microRNA 133a-1; targeted mutation 1.1, Eric N Olson |
MGI ID: |
MGI:3822154 |
Synonyms: |
Mirn133a-1ko |
Gene: |
Mir133a-1 Location: Chr18:10782909-10782976 bp, - strand Genetic Position: Chr18, 5.4 cM
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Alliance: |
Mir133a-1tm1.1Eno page
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Germline Transmission: |
Earliest citation of germline transmission:
J:142220
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S/SvEv
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The 68 bp pre-miR stem loop found in intron 23 of Mib1 was replaced by an FRT flanked neomycin resistance cassette. Mib1 expression is not affected. Mice derived from correctly targeted ES cells were crossed to Tg(ACTFLPe)9205Dym mice to excise the neomycin selection cassette.
(J:142220)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mir133a-1 Mutation: |
2 strains or lines available
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Original: |
J:142220 Liu N, et al., microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev. 2008 Dec 1;22(23):3242-54 |
All: |
5 reference(s) |
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