Slc2a3^Gt(XG611)Byg
Gene trapped Allele Detail

Summary

• Symbol: Slc2a3^Gt(XG611)Byg
• Name: solute carrier family 2 (facilitated glucose transporter), member 3; gene trap XG611, BayGenomics
• MGI ID: MGI:3822325
• Gene: Slc2a3 Location: Chr6:122704768-122778599 bp, - strand Genetic Position: Chr6, 57.82 cM
• Alliance: Slc2a3^Gt(XG611)Byg page

Mutation origin

• Mutant Cell Line: XG611
• Germline Transmission: Earliest citation of germline transmission: J:142763
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: Gene trap vector pGT1Lxf was inserted in intron 1. Levels of mRNA were reduced 50% in the brain and testes of heterozygotes. (J:142763)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XG611	CC182775 ; (MGI Seq Detail)	5' RACE	Chr6:122719336-122719477 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  218 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:

11 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc2a3 Mutation: 43 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:142763 Schmidt S, et al., Neuronal functions, feeding behavior, and energy balance in Slc2a3+/- mice. Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1084-94
• All: 3 reference(s)