Tg(Lhb-cre)1Sac
Transgene Detail

Summary

• Symbol: Tg(Lhb-cre)1Sac
• Name: transgene insertion 1, Sally A Camper
• MGI ID: MGI:3822455
• Transgene: Tg(Lhb-cre)1Sac Location: unknown
• Alliance: Tg(Lhb-cre)1Sac page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Lhb-cre)1Sac expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  cattle	LHB (280839)

• Mutation details: The bovine gonadotrope-specific enhancer was used to drive expression of an EGFP/cre fusion gene in the pituitary cells that produce luteinizing hormone beta. No GFP signal could be detected in the one mouse line created. (J:142726)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	LHB (cattle) Summary of all recombinase alleles driven by LHB. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:142726 Charles MA, et al., Pitx2 deletion in pituitary gonadotropes is compatible with gonadal development, puberty, and fertility. Genesis. 2008 Oct;46(10):507-14
• All: 8 reference(s)