Septin3^tm1Wtr
Targeted Allele Detail

Summary

• Symbol: Septin3^tm1Wtr
• Name: septin 3; targeted mutation 1, William S Trimble
• MGI ID: MGI:3822551
• Gene: Septin3 Location: Chr15:82153003-82178775 bp, + strand Genetic Position: Chr15, 38.56 cM, cytoband E2
• Alliance: Septin3^tm1Wtr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:142823
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 through 5 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on bain extracts. (J:142823)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Septin3 Mutation: 25 strains or lines available

References

• Original: J:142823 Tsang CW, et al., Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission. Mol Cell Biol. 2008 Dec;28(23):7012-29
• All: 1 reference(s)