Nmu^tm1Sjab
Targeted Allele Detail

Summary

• Symbol: Nmu^tm1Sjab
• Name: neuromedin U; targeted mutation 1, Susan J Abbondanzo
• MGI ID: MGI:3822775
• Gene: Nmu Location: Chr5:76481342-76511624 bp, - strand Genetic Position: Chr5, 40.93 cM
• Alliance: Nmu^tm1Sjab page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:142907
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Position 36-207 of the open reading frame of gene (NM_019515) was deleted and replaced with a IRES-LacZ-Neo cassette. Disruption of gene transcription was confirmed by Northern blotting of stomach and small intestine RNA. (J:142907)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nmu Mutation: 20 strains or lines available

References

• Original: J:142907 Abbondanzo SJ, et al., Nmur1-/- mice are not protected from cutaneous inflammation. Biochem Biophys Res Commun. 2009 Jan 23;378(4):777-82
• All: 1 reference(s)