Tg(Ckm-Lamb2)1Jhm
Transgene Detail

Summary

• Symbol: Tg(Ckm-Lamb2)1Jhm
• Name: transgene insertion 1, Jeffrey H Miner
• MGI ID: MGI:3826355
• Synonyms: MCK-B2
• Transgene: Tg(Ckm-Lamb2)1Jhm Location: unknown
• Alliance: Tg(Ckm-Lamb2)1Jhm page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ckm-Lamb2)1Jhm expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Lamb2 (25473)

  Lamb2

  (MGI:99916)

• Mutation details: The mouse promoter was used to drive muscle specific expression of the rat gene. Two lines were created but only one line (designated as line 1) exhibited expression in muscle synapses. (J:106005)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:106005 Miner JH, et al., Transgenic isolation of skeletal muscle and kidney defects in laminin {beta}2 mutant mice: implications for Pierson syndrome. Development. 2006 Mar;133(5):967-75
• All: 6 reference(s)