Rhohtm1Brak
Targeted Allele Detail
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| Symbol: |
Rhohtm1Brak |
| Name: |
ras homolog family member H; targeted mutation 1, Cord Brakebusch |
| MGI ID: |
MGI:3826431 |
| Synonyms: |
RhoH- |
| Gene: |
Rhoh Location: Chr5:66018556-66054043 bp, + strand Genetic Position: Chr5, 33.8 cM, cytoband D
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| Alliance: |
Rhohtm1Brak page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:143161
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A 0.9 kb fragment encoding the first 42 amino acids was replaced with a neomycin resistance cassette. This removes the translation start site and the switch 1 region. Northern blot analysis indicated that no normal protein was expressed.
(J:143161)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Rhoh Mutation: |
13 strains or lines available
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| Original: |
J:143161 Dorn T, et al., RhoH is important for positive thymocyte selection and T-cell receptor signaling. Blood. 2007 Mar 15;109(6):2346-55 |
| All: |
5 reference(s) |
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Analysis Tools
