Tg(Myh6-F2r)18Nmk
Transgene Detail

Summary

• Symbol: Tg(Myh6-F2r)18Nmk
• Name: transgene insertion 18, Nigel Mackman
• MGI ID: MGI:3826819
• Transgene: Tg(Myh6-F2r)18Nmk Location: unknown
• Alliance: Tg(Myh6-F2r)18Nmk page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-F2r)18Nmk expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	F2r (MGI:101802)

• Mutation details: A mouse F2r cDNA sequence was place under the conrol of the Myh6 promoter. Elevated F2r expression was detected in the heart by Western blot and was localized to the plasma membrane, intercalating discs and cytoplasm of cardiomyocytes. (J:142990)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:142990 Pawlinski R, et al., Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy. Circulation. 2007 Nov 13;116(20):2298-306
• All: 2 reference(s)