Egfl7^tm1.1Cjku
Targeted Allele Detail

Summary

• Symbol: Egfl7^tm1.1Cjku
• Name: EGF-like domain 7; targeted mutation 1.1, Calvin J Kuo
• MGI ID: MGI:3826822
• Synonyms: Egfl7^delta
• Gene: Egfl7 Location: Chr2:26471095-26482694 bp, + strand Genetic Position: Chr2, 18.95 cM, cytoband B
• Alliance: Egfl7^tm1.1Cjku page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143206
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 5 through 7 were removed by germ line, cre mediated recombination. The absence of transcript expression and presence of Mirn126 transcript expression was confirmed by quantitative PCR on embryo extracts. The absence of protein expression was confirmed by immunohistochemistry of adult tissue. (J:143206)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Egfl7 Mutation: 17 strains or lines available

References

• Original: J:143206 Kuhnert F, et al., Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126. Development. 2008 Dec;135(24):3989-93
• All: 1 reference(s)