Tg(Myh6-F3)4Nmk
Transgene Detail

Summary

• Symbol: Tg(Myh6-F3)4Nmk
• Name: transgene insertion 4, Nigel Mackman
• MGI ID: MGI:3826845
• Transgene: Tg(Myh6-F3)4Nmk Location: unknown
• Alliance: Tg(Myh6-F3)4Nmk page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-F3)4Nmk expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  F3 (2152)

  F3	(MGI:88381)

• Mutation details: F3 expression was placed under the control of the Myh6 promoter. This results in 14-16 fold overexpression in cardiac myocytes as well as expression in pulmonary veins and venules. (J:137921)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:137921 Pawlinski R, et al., Role of cardiac myocyte tissue factor in heart hemostasis. J Thromb Haemost. 2007 Aug;5(8):1693-700
• All: 1 reference(s)