Bsnd^tm1.1Tjj
Targeted Allele Detail

Summary

• Symbol: Bsnd^tm1.1Tjj
• Name: barttin CLCNK type accessory beta subunit; targeted mutation 1.1, Thomas J Jentsch
• MGI ID: MGI:3826850
• Gene: Bsnd Location: Chr4:106340653-106349440 bp, - strand Genetic Position: Chr4, 49.67 cM
• Alliance: Bsnd^tm1.1Tjj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143314
• Parent Cell Line: MPI-II (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove exon 2. This deletion results in a stop codon at position 74. (J:143314)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bsnd Mutation: 16 strains or lines available

References

• Original: J:143314 Rickheit G, et al., Endocochlear potential depends on Cl- channels: mechanism underlying deafness in Bartter syndrome IV. EMBO J. 2008 Nov 5;27(21):2907-17
• All: 1 reference(s)