Hccs^tm1Tcc
Targeted Allele Detail

Summary

• Symbol: Hccs^tm1Tcc
• Name: holocytochrome c synthetase; targeted mutation 1, Timothy C Cox
• MGI ID: MGI:3826866
• Gene: Hccs Location: ChrX:168094526-168103361 bp, - strand Genetic Position: ChrX, 78.98 cM
• Alliance: Hccs^tm1Tcc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143285
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 5 and a neo cassette with a 3' loxP site was inserted downstream of exon 7. (J:143285)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Hccs Mutation: 4 strains or lines available

References

• Original: J:143285 Drenckhahn JD, et al., Compensatory growth of healthy cardiac cells in the presence of diseased cells restores tissue homeostasis during heart development. Dev Cell. 2008 Oct;15(4):521-33
• All: 4 reference(s)