Vegfd^tm1Hrl
Targeted Allele Detail

Summary

• Symbol: Vegfd^tm1Hrl
• Name: vascular endothelial growth factor D; targeted mutation 1, H R Lijnen
• MGI ID: MGI:3826978
• Synonyms: VEGF-D^-, Vegf-d⁰
• Gene: Vegfd Location: ChrX:163156374-163185646 bp, + strand Genetic Position: ChrX, 76.35 cM
• Alliance: Vegfd^tm1Hrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143070
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 through 4 were replaced with a lacZ gene and floxed neo cassette. The absence of transcript expression was confirmed by RT-PCR on lung extracts. (J:153734)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vegfd Mutation: 15 strains or lines available

References

• Original: J:143070 Lijnen HR, et al., Deficiency of vascular endothelial growth factor-D does not affect murine adipose tissue development. Biochem Biophys Res Commun. 2009 Jan 9;378(2):255-8
• All: 2 reference(s)