Tg(Hmgcr-lacZ)H253Sest
Transgene Detail

Summary

• Symbol: Tg(Hmgcr-lacZ)H253Sest
• Name: transgene insertion H253, Seong-Seng Tan
• MGI ID: MGI:3826981
• Synonyms: HMG CoA lacZ
• Transgene: Tg(Hmgcr-lacZ)H253Sest Location: unknown Genetic Position: ChrX, Syntenic
• Alliance: Tg(Hmgcr-lacZ)H253Sest page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Tg(Hmgcr-lacZ)H253Sest expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Hmgcr (MGI:96159)

• Mutation details: The mouse promoter was used to drive ubiquitous expression of lacZ that is X-linked due to the insertion of the transgene into the X chromosome. Line H253 carried 14 tandem copies of the transgene. (J:3863)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:3863 Tan SS, et al., X-chromosome inactivation occurs at different times in different tissues of the post-implantation mouse embryo [published erratum appears in Nat Genet 1993 Jul;4(3):320]. Nat Genet. 1993 Feb;3(2):170-4
• All: 8 reference(s)