Zfp57^tm1Xjli
Targeted Allele Detail

Summary

• Symbol: Zfp57^tm1Xjli
• Name: zinc finger protein 57; targeted mutation 1, Xiajun Li
• MGI ID: MGI:3826983
• Gene: Zfp57 Location: Chr17:37312055-37321527 bp, + strand Genetic Position: Chr17, 19.16 cM, cytoband B3
• Alliance: Zfp57^tm1Xjli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143283
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An frt-flanked neo-zeo cassette with a 5' loxP site was inserted upstream of exon 2 and an additional loxP site was inserted downstream of exon 3. The selection cassette was removed by transient flp expression in ES cells. (J:143283)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp57 Mutation: 41 strains or lines available

References

• Original: J:143283 Li X, et al., A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints. Dev Cell. 2008 Oct;15(4):547-57
• All: 1 reference(s)