Zfp57^tm1.1Xjli
Targeted Allele Detail

Summary

• Symbol: Zfp57^tm1.1Xjli
• Name: zinc finger protein 57; targeted mutation 1.1, Xiajun Li
• MGI ID: MGI:3826984
• Gene: Zfp57 Location: Chr17:37312055-37321527 bp, + strand Genetic Position: Chr17, 19.16 cM, cytoband B3
• Alliance: Zfp57^tm1.1Xjli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143283
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were removed by germ line, cre mediated recombination or transient cre expression in ES cells. The absence of expression of the full-length transcript and expression of a truncated one was confirmed by northern blot analysis on E12.5 embryo extracts. (J:143283)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp57 Mutation: 41 strains or lines available

References

• Original: J:143283 Li X, et al., A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints. Dev Cell. 2008 Oct;15(4):547-57
• All: 4 reference(s)