Gstm1^tm1Kfuj
Targeted Allele Detail

Summary

• Symbol: Gstm1^tm1Kfuj
• Name: glutathione S-transferase, mu 1; targeted mutation 1, Kazunori Fujimoto
• MGI ID: MGI:3828070
• Gene: Gstm1 Location: Chr3:107919571-107925289 bp, - strand Genetic Position: Chr3, 46.83 cM, cytoband F3
• Alliance: Gstm1^tm1Kfuj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143553
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire gene, exons 1 through 8, was replaced with a neomycin selection cassette. No mRNA was detected in the liver of homozygotes by RT-PCR. (J:143553)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gstm1 Mutation: 25 strains or lines available

References

• Original: J:143553 Fujimoto K, et al., Characterization of phenotypes in Gstm1-null mice by cytosolic and in vivo metabolic studies using 1,2-dichloro-4-nitrobenzene. Drug Metab Dispos. 2006 Sep;34(9):1495-501
• All: 1 reference(s)