Sall2^tm1Jkoh
Targeted Allele Detail

Summary

• Symbol: Sall2^tm1Jkoh
• Name: spalt like transcription factor 2; targeted mutation 1, Jurgen Kohlhase
• MGI ID: MGI:3828110
• Gene: Sall2 Location: Chr14:52548634-52566127 bp, - strand Genetic Position: Chr14, 26.89 cM, cytoband B-C1
• Alliance: Sall2^tm1Jkoh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143350
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1a and 2 were replaced with a neo cassette via homologous recombination. Northern blot analysis confirmed the absence of RNA expression in kidneys from homozygous mice. (J:143350)

Expression

In Mice Carrying this Mutation:	26 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sall2 Mutation: 51 strains or lines available

References

• Original: J:143350 Bohm J, et al., Sall1, sall2, and sall4 are required for neural tube closure in mice. Am J Pathol. 2008 Nov;173(5):1455-63
• All: 2 reference(s)