Vgf^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Vgf^tm1Vlcg
• Name: VGF nerve growth factor inducible; targeted mutation 1, Velocigene
• MGI ID: MGI:3828156
• Gene: Vgf Location: Chr5:137055246-137062205 bp, + strand Genetic Position: Chr5, 76.13 cM
• Alliance: Vgf^tm1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143370
• Parent Cell Line: F1H4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• The entire coding region was replaced with a lacZ reporter and neo cassette. (J:102090, J:143370, J:212045)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vgf Mutation: 26 strains or lines available

References

• Original: J:143370 Bozdagi O, et al., The neurotrophin-inducible gene Vgf regulates hippocampal function and behavior through a brain-derived neurotrophic factor-dependent mechanism. J Neurosci. 2008 Sep 24;28(39):9857-69
• All: 6 reference(s)