Pde6a^nmf363
Chemically induced Allele Detail

Summary

• Symbol: Pde6a^nmf363
• Name: phosphodiesterase 6A, cGMP-specific, rod, alpha; neuroscience mutagenesis facility, 363
• MGI ID: MGI:3828520
• Synonyms: NMF363
• Gene: Pde6a Location: Chr18:61353387-61422995 bp, + strand Genetic Position: Chr18, 34.41 cM
• Alliance: Pde6a^nmf363 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis was used to create an A to G transition that results in an amino acid substitution of glycine for aspartic acid at position 670 (D670G). (J:142108)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pde6a Mutation: 52 strains or lines available

References

• Original: J:142108 Sakamoto K, et al., New mouse models for recessive retinitis pigmentosa caused by mutations in the Pde6a gene. Hum Mol Genet. 2009 Jan 1;18(1):178-92
• All: 10 reference(s)